Publications

Florence Atrafi, Herlinde Dumez, Ron H.J. Mathijssen, Catharine W Menke van der Houven van Oordt, Cristianne J.F. Rijcken, Rob Hanssen, Ferry A.L.M. Eskens, Patrick Schöffski
A phase I dose-escalation and pharmacokinetic study of a micellar nanoparticle with entrapped docetaxel (CPC634) in patients with advanced solid tumours
Journal of Controlled Release 2020

Irina Alberg, Stefan Kramer, Meike Schinnerer, Qizhi Hu, Christine Seidl, Christian Leps, Natascha Drude, Diana Möckel, Cristianne Rijcken, Twan Lammers, Mustafa Diken, Michael Maskos, Svenja Morsbach, Katharina Landfester, Stefan Tenzer, Matthias Barz, Rudolf Zente
Polymeric Nanoparticles with Neglectable Protein Corona
Small 2020

Iris H.C. Miedema, Gerben J.C. Zwezerijnen, Daniela E. Oprea-Lager, Henk M.W. Verheul, Danielle
J. Vugts, Marc C. Huisman, Ron H.J. Mathijssen, Cristianne J.F. Rijcken, Qizhi Hu, G.a.M.S. van
Dongen, Catharina Wilhelmina Menke;
First-in-human imaging of nanoparticle entrapped docetaxel (CPC634) in patients with advanced solid tumors using 89Zr-Df-CPC634 PET/CT
ASCO 2019, Abstract #254871

Florence Atrafi, Ruben A.G. van Eerden, Marte A.M. van Hylckama Vlieg, Esther Oomen De Hoop,
Peter de Bruijn, Cristianne J.F. Rijcken, Rob Hanssen, Ferry Eskens, Ron H.J. Mathijssen, Stijn L.W.
Koolen
Nanoparticle entrapped docetaxel (CPC634) enhances intratumoral docetaxel exposure compared to conventional docetaxel (Cd) in patients with solid tumors
ASCO 2019, Abstract #255937

Florence Atrafi, Herlinde Dumez, Ron H.J. Mathijssen, Catharina Wilhelmina Menke, Jo Costermans,
Cristianne J.F. Rijcken, Rob Hanssen, Ferry Eskens, Patrick Schoffski
A phase I dose-finding and pharmacokinetics study of CPC634 (nanoparticle entrapped docetaxel) in patients with advanced solid tumors
ASCO 2019, Abstract #254877

CL Braal, P de Bruijn, F Atrafi, M van Geijn, CJF Rijcken, RHJ Mathijssen, SLW Koolen
New method for the determination of total and released docetaxel from docetaxel-entrapped core-crosslinked polymeric micelles (CriPec^®) by LC–MS/MS and its clinical application in plasma and tissues in patients with various tumours
Journal of Pharmaceutical and Biomedical Analysis 2018

Q Hu, J Prakash, CJF Rijcken, WE Hennink, G Storm
High systemic availability of nanomedicines based on core-cross-linked polymeric micelles after subcutaneous administration
International Journal of Pharmaceutics 2016

Q Hu, CJF Rijcken, EVB van Gaal, P Brundel, H Kostkova, T Etrych, B Weber, M Barz, F Kiessling, J Prakash, G Storm, WE Hennink, T Lammers
Tailoring the physicochemical properties of core-crosslinked polymeric micelles for pharmaceutical applications
Journal of Controlled Release 2016

Q Hu, CJF Rijcken, R Bansal, WE Hennink, G Storm, J Prakash
Complete regression of breast cancer with a single dose of docetaxel-entrapped core-crosslinked polymeric micelles
Biomaterials 2015

Q Hu, EVB van Gaal, P Brundel, H Ippel, T Hackeng, CJF Rijcken, G Storm, WE Hennink, J Prakash
A novel approach for the intravenous delivery of leuprolide using core-cross-linked polymeric micelles
Journal of Controlled Release 2015

M Talelli, Matthias Barz, CJF Rijcken, F Kiessling, WE Hennking, T Lammers
Core-crosslinked polymeric micelles: principles, preparation, biomedical applications and clinical translation
Nano Today 2015

L Quan, Y Zhang, BJ Crielaard, A Dusad, SM Lele, CJF Rijcken, JM Metselaar, H Kostková, T Etrych, K Ulbrich, F Kiessling, TR Mikuls, WE Hennink, G Storm, T Lammers, D Wang
Nanomedicines for inflammatory arthritis: head-to-head comparison of glucocorticoid-containing polymers, micelles and liposomes
ACS Nano 2014

M Talelli, CJF Rijcken, WE Hennink, T Lammers
Polymeric micelles for cancer therapy: 3 C’s to enhance efficacy
Current Opinion in Solid State and Materials Science 2012

M Coimbra, CJF Rijcken, M Stigter, WE Hennink, G Storm, RM Schiffelers
Antitumor efficacy of dexamethasone-loaded core-crosslinked polymeric micelles
Journal of Controlled Release 2012

M Talelli, S Oliveira, CJF Rijcken, E Pieters, T Etrych, K Ulbrich, CF van Nostrum, G Storm, WE Hennink, T Lammers
Intrinsically active nanobody-modified polymeric micelles for tumor-targeted combination therapy
Biomaterials 2012

BJ Crielaard, CJF Rijcken, LD Quan, M van der Pot, I Altintas, S van der Wal, RMJ Liskamp, RM Schiffelers, CF van Nostrum, WE Hennink, D Wang, T Lammers, G. Storm
Glucocorticoid loaded core cross linked polymeric micelles with tailorable release kinetics for targeted therapy of rheumatoid arthritis
Angewandte Chemie 2012

M Talelli, CJF Rijcken, S Oliveira, R van Meel, PMP van Bergen en Henegouwen, CF van Nostrum, T Lammers, G Storm and WE Hennink
Nanobody – shell functionalized thermosensitive polymeric micelles for active targeting
Journal of Controlled Release 2011

M Talelli, K Morita, CJF Rijcken, RWM Aben, T Lammers, HW Scheeren, CF van Nostrum, T Lammers, G Storm and WE Hennink
Synthesis and characterization of biodegradable and thermosensitive polymeric micelles with covalently bound doxorubicin-glucuronide prodrug via click chemistry
Bioconjugate Chemistry 2011

M Coimbra, B Isacchi, L van Bloois, J Sastre Torano, A Ket, X Wu, F Broere, JM Metselaar, CJF Rijcken, G Storm, R Bilia and RM Schiffelers
Improving solubility and chemical stability of natural compounds for medicinal use by incorporation into liposomes
International Journal of Pharmaceutics 2011

M Talelli, CJF Rijcken, S Oliveira, R van Meel, PMP van Bergen en Henegouwen, CF van Nostrum, T Lammers, G Storm and WE Hennink
Nanobody – shell functionalized thermosensitive polymeric micelles for active targeting
Journal of Controlled Release 2011

M Talelli, M Iman, AK Varkouhi, CJF Rijcken, RM Schiffelers, T Etrych, K Ulbrich, CF van Nostrum, T Lammers, G Storm, WE Hennink
Core-crosslinked polymeric micelles with controlled release of covalently entrapped doxorubicin: preparation, characterisation and in vivo efficacy
Biomaterials 2010

CJF Rijcken, M Talelli, CF van Nostrum, G Storm, WE Hennink
Therapeutic Nanomedicine: Cross linked micelles with transiently linked drugs–a versatile drug delivery system
European Journal of Nanomedicine 2010

M Talelli, CJF Rijcken, CF van Nostrum, G Storm, WE Hennink
Micelles based on HPMA copolymers
Advanced Drug Delivery Reviews 2009

M Talelli, CJF Rijcken, T Lammers, P Seevinck, G Storm, CF van Nostrum, WE Hennink
Superparamagnetic iron oxide nanoparticles encapsulated in biodegradable thermosensitive polymeric micelles: Towards a targeted nanomedicine suitable for image-guided drug delivery
Langmuir 2009

PM van Hasselt, GEPJ Janssens, TK Slot, M van der Ham, TC Minderhoud, LM Akkermans, CJF Rijcken, CF van Nostrum
The influence of bile acids on the absorption of vitamin K encapsulated in polymeric micelles
Journal of Controlled Release 2008

A Ramzi, CJF Rijcken, TFJ Veldhuis, D Schwahn, WE Hennink and CF van Nostrum
Core-shell structure of degradable, thermosensitive polymeric micelles studied by small-angle neutron scattering
Journal of Physical Chemistry B 2008

CJF Rijcken, MG Carstens, CF van Nostrum and WE Hennink
Pharmaceutical Micelles: Combining longevity, stability and stimuli-sensitivity
Book: Multifunctional pharmaceutical nanocarriers 2008 Chapter 9

CJF Rijcken, CJ Snel, RM Schiffelers, CF van Nostrum and WE Hennink
Hydrolysable core crosslinked thermosensitive polymeric micelles: synthesis, characterisation and in vivo studies
Biomaterials 2007

CJF Rijcken, JW Hofman, F van Zeeland, CF van Nostrum and WE Hennink
Formulation of Si(sol)2Pc in polymeric micelles: a chacterisation and in vitro PDT efficacy study
Journal of Controlled Release 2007

CJF Rijcken, O Soga, WE Hennink and CF van Nostrum
Triggered destabilisation of polymeric micelles and vesicles by changing polymers polarity: an attractive tool for drug delivery
Journal of Controlled Release 2007

CJF Rijcken, M Leemhuis, TFJ Veldhuis, WE Hennink and CF van Nostrum
Step-by-step synthesis of monodisperse methacrylamidoalkyl oligolactates
Macromolecular Rapid Communications 2006

CJF Rijcken, TFJ Veldhuis, A Ramzi, JD Meeldijk, CF van Nostrum and WE Hennink
Novel fast degradable thermosensitive polymeric micelles based on PEG-block-poly(N-(2-hydroxyethyl)methacrylamide-oligolactates)
Biomacromolecules 2005

Soga, CF van Nostrum, M Fens, CJF Rijcken, RM Schiffelers, G Storm and WE Hennink
Thermosensitive and biodegradable polymeric micelles for paclitaxel delivery
Journal of Controlled Release 2005