Supervisory board

Dr. Joost Holthuis, an entrepreneur in the life sciences, is a co-founder and former CEO of Cristal Therapeutics. Dr. Holthuis started his career in 1988 at Chiron in analytical and product development. He subsequently founded OctoPlus in 1995 where he was the CEO for 14 years. During that time, he built up and successfully listed the company on Euronext. OctoPlus was acquired by Dr. Reddy’s in 2013.

In 2010 he became involved in Cristal Therapeutics. He is active in the board of various start-up companies and has been involved in BioGenerationVentures as venture partner for over 8 years.

Dr. Holthuis received an M.Sc. in Pharmaceutical Sciences and a Pharmacist degree from the University of Leiden and he holds a Ph.D. from the University of Utrecht.

Dr. Krul is the founder and a partner of Aglaia BioMedical Ventures.

He has been involved in anticancer drug development since 1993 and has a background in molecular biology and immunology.

Before founding Aglaia BioMedical Ventures in 2003 he was Program Director of the NDDO Research Foundation. He held several positions at NDDO Oncology BV (formerly the EORTC New Drug Development Office) with respect to oncology drug development strategies (1997-2002). From 1993 till 199.

Dr. Krul was Research Manager of the European Cancer Center and headed the Department of Molecular Virology at the National Institute of Public Health and Environmental Protection from 1989 till 1993.

Dr. Kloosterman is (senior) investment manager for DSM Venturing (DSM’s corporate investment group), Limburg Ventures and Chemelot Ventures (both funds co-founded by DSM Nederland with regional focus). He has worked at DSM NV in various positions since 1985.

Dr. Kloosterman focuses on breakthrough private and listed companies in the areas of Life Sciences and Performance Materials that are looking for equity financing. He serves in non-executive boards of several European startup companies, and acts as advisory board member or jury member in several European panels.

Dr. Kloosterman holds a PhD in Organic Chemistry from Leiden University.